Conclusions: There was clinically meaningful improvement in depth of response with Isa-Kd. CR rate
in Isa-Kd was 39.7%. Mass spectrometry suggests that the potential adjusted CR rate could reach 45.8%
of pts treated in Isa-Kd. More pts in Isa-Kd vs Kd reached MRD- (29.6% vs 13.0%) and at least twice as
many reached CR MRD- (adjusted 24.0% vs 10.6%).