del(11)(q23) and might be revised mainly in the IPSS-R. Thus, our results indicate the need for
more cytogenetic studies.
Conclusion: Cytogenetic analysis aided in the diagnosis of cases with suspected pediatric MDS
and it was an important tool for the choice of treatment. Our results showed that -7,
del(11)(q23), and complex karyotypes have an impact on the disease evolution. Our study
provides new information into the role of the chromosomal abnormalities in pediatric MDS
with important clinical implications.
