SCIENTIFIC PROGRAMME
SESSION I
BIOLOGY OF B-CELL
PRECURSOR ALL
SESSION II
BIOLOGY OF T-CELL ALL
SESSION III
MINIMAL RESIDUAL
DISEASE MONITORING
SESSION IV
INDIVIDUALIZED
MANAGEMENT OF ALL
SESSION V
NEW ADVANCES IN ALL
SESSION VI
CAR T-CELLS &
ALLOGENEIC HSCT
SESSION VII
FRONTLINE
INCORPORATION OF
BITES AND ADCS
SESSION VIII
T-CELL ALL AND
LYMPHOBLASTIC
LYMPHOMA
SESSION IX
PH AND PH-LIKE ALL
SELECTED ABSTRACTS
FOR AN ORAL
PRESENTATION
SELECTED ABSTRACTS
AS E-POSTERS
DISCLOSURES
Poster 18: CHARACTERIZATION OF MOLECULAR MECHANISM RESPONSIBLE FOR
FLT3 GENE OVEREXPRESSION IN ACUTE LEUKEMIAS
Caroline Pires Poubel, Ana Luiza Tardem Maciel, Thayana Barbosa, Marcela
B. Mansur, Mariana Boroni, Mariana Emerenciano
Poster 19: DASATINIB AND NAVITOCLAX REVERSE GLUCOCORTICOID
RESISTANCE IN PRE-T-CELL RECEPTOR ACTIVATED T-CELL ACUTE
LYMPHOBLASTIC LEUKAEMIA
Alistair Poll, Yuzhe Shi, Hayden Bell, Edward Law, Julie Irving, Frederik van
Delft
Poster 20: Ph+ ALL CELL LINE WITH PTPN11 MUTATIONS IS RESISTANT TO ALL
TKIs AS WELL AS VENETOCLAX BUT SENSITIVE TO THE COMBINATION
Govinda Poudel, Kartini Asari, David T Yeung, Deborah L. White, Timothy P.
Hughes, Ilaria S Pagani
Poster 21: AURORA KINASES AS CANDIDATE TARGETS FOR T CELL ACUTE
LYMPHOBLASTIC LEUKEMIA TREATMENT
Cristina Prieto, Kris Jacobs, Olga Gielen, Patricia Altea, Sofie Demeyer, Sarah
Provost, Jan Cools
Poster 22: CO-TARGETING BCL-2- AND PI3K/AKT-PATHWAYS REVEALS
SYNERGISTIC EFFECTS IN ACUTE B-LYMPHOBLASTIC LEUKEMIA CELLS
Anna Richter, Clemens Holz, Anett Sekora, Sandra Lange, Christian Junghanss
Poster 23: DIRECT INTERACTION OF MSC WITH B-ALL CELLS PROMOTES THE
ACTIVATION OF NF-Kb SIGNALLING, HOWEVER SENSITIZATION TO
CHEMOTHERAPY OF LEUKEMIC CELLS DEPENDS ON STROMAL PKC
INHIBITION.
Paola Fernanda Ruiz-Aparicio, Gloria-Inés Uribe, Adriana Linares-Ballesteros,
Jean-Paul Vernot
Poster 24: USING WHOLE GENOME SEQUENCING TO IDENTIFY BESPOKE DNA
MEASURABLE RESIDUAL DISEASE MARKERS IN ACUTE
LYMPHOBLASTIC LEUKAEMIA
Georgina Ryland, Ing Soo Tiong, Ashish Bajel, Ashley Ng, Paul Ekert, David
Westerman, Sean Grimmond, Piers Blombery
Poster 25: ONCOGENIC COOPERATION BETWEEN TAL1 EXPRESSION AND
PI3K/AKT PATHWAY ACTIVATION IN T-CELL ACUTE LYMPHOBLASTIC
LEUKEMIA
Naomi Thielemans, Sofie Demeyer, Nicole Mentens, Sarah Provost, Olga
Gielen, Jan Cools
Poster 26: B-CELL PRECURSOR ALL INDUCED SENESCENCE AND ABNORMAL
STEMNESS PROPERTIES IN MESENCHYMAL STEM CELLS.
Natalia del Pilar Vanegas, Gloria-Inés Uribe, Adriana Linares-Ballesteros,
Jean-Paul Vernot