SESSION III – Dyserythropoiesis in clonal haemopoiesis and MDS
Chairs: Valeria Santini (Florence), Michaela Fontenay (Paris)
18:10-18:15 Introduction Valeria Santini (Florence)
Michaela Fontenay (Paris)
18:15-18:30 Into the mechanisms of dyserythropoiesis :
the SF3B1mutation and RSP-14 deficiency models Michaela Fontenay (Paris)
18:30-18:45 TGF pathway in ineffective erythropoiesis Olivier Hermine (Paris)
18:45-19:00 Hypoxic niche and microenvironment in clonal
haemopoiesis and MDS Marc H.G.P. Raaijmakers (Rotterdam)
19:00-19:07 Why is the translation selectivity of low ribosome Ismael Boussaid (Paris)
availability deleterious for erythropoiesis?
19:07-19:40 Panel discussion
19:40-20:40 3 Simultaneous Meet the Expert Sessions
1. Management of non-transfusion-dependent thalassaemias Ali Taher (Beirut)/John Porter (London)
2. New treatments in haemoglobinopathies Antonio Piga (Turin)
3. Anaemia and autoimmunity management in MDS. Pierre Fenaux (Paris)/Arsene Mekinian (Paris)
2
Saturday, March 6th, 2021
SCIENTIFIC PROGRAMME
SESSION I
BONE MARROW
RESPONSE TO VIRAL
INFECTIONS
SESSION II
HAEMATOLOGICAL
RESPONSE TO SARS
COV2 INFECTION
SESSION III
DYSERYTHROPOIESIS IN
CLONAL HAEMOPOIESIS
AND MDS
SESSION IV
ERYTHROPOIESIS
CONTROL
SESSION V
ERYTHROPOIESIS
CONTROL : PHASE 2
SESSION IV – Erythropoiesis Control
Chairs: Douglas Higgs (Oxford), Mark Fleming (Boston)
13:30-13:35 Introduction Douglas Higgs (Oxford)
SESSION VI
Mark Fleming (Boston)
IRON METABOLISM
AND ERYTHROPOIESIS
13:35-13:50 Congenital sideroblastic anaemias Mark Fleming (Boston)
13:50-14:05 GATA 1 experience Emery Bresnick (Madison)
SESSION VII
INHERITED
14:05-14:20 Single cell analysis during erythropoiesis Vijay G. Sankaran (Boston)
DYSERYTHROPOIESIS
14:20-14:27 Acquired α-Thalassemia (HbH disease) in a Patient
with Myelodysplastic Syndrome with Excess Blasts - 1
(AT-MDS-EB-1) Reveals a Novel Splice-Donor Site Atrx
SESSION VIII
variant on NGS Prashant Sharma (Chandigarh)
GENE THERAPY/EDITION
14:27-15:00 Panel discussion
SESSION V – Erythropoiesis control : phase 2
SESSION IX – DRUGS
Chairs: Mohandas Narla (New York), Stuart Orkin (Boston)
AND INEFFECTIVE
ERYTHROPOIESIS
15:00-15:05 Introduction Mohandas Narla (New York)
Stuart Orkin (Boston)
SELECTED ABSTRACTS
15:05-15:20 Erythroid progenitors Lionel Blanc (New York)
FOR AN ORAL
PRESENTATION
15:20-15:35 Eryptosis Mehrdad Ghashghaeinia (Tübingen)
SELECTED ABSTRACTS
FOR A POSTER
PRESENTATION
FACULTY DISCLOSURES