SCIENTIFIC PROGRAMME
SESSION I
THE GENOMIC AND
EPIGENOMIC LANDSCAPE
OF CLL AND CLINICAL
CONSEQUENCES
SESSION II
THE ROLE OF BCR
ACTIVATION AND
SIGNALLING FOR CLL
SESSION III
THERAPEUTIC OPTIONS
FOR CLL
SESSION IV
LONG TERM FOLLOW
UP OF CLINICAL TRIALS
VERSUS REAL WORLD
DATA (OUTSIDE CLINICAL
TRIALS DATA-OCT)
SESSION V
THE INCREASING ROLE
OF THE LEUKAEMIC
MICROENVIRONMENT
SESSION VI
THERAPEUTIC OPTIONS 2 :
THE USE OF CELLULAR
AND NON-CELLULAR
IMMUNOTHERAPIES IN
CLL
SESSION VII
EFFICACY THROUGH
SAFETY
SESSION VIII
CLONAL HETEROGENEITY,
CLONAL EVOLUTION AND
MECHANISMS OF DRUG
RESISTANCE
SESSION IX
CONTRASTING
THERAPEUTIC CONCEPTS
SELECTED ABSTRACTS
FOR AN ORAL
PRESENTATION
SELECTED ABSTRACTS
FOR A POSTER
PRESENTATION
FACULTY DISCLOSURES
Poster 8: DETECTION OF CLL-TYPE STEREOTYPED BCR BY HIGH THROUGHPUT
SEQUENCING IN HEALTHY PEOPLE WITHOUT ANY HEMATOLOGICAL PAST
HISTORY
Marine Dupont, Alexis Saint-Amand, Paco Derouault, Mélanie Boulin, Nataliya
Dmytruk, Jasmine Chauzeix, Jean Feuillard, Nathalie Gachard and David Rizzo
Poster 9: DECIPHERING CHRONIC LYMPHOCYTIC LEUKEMIA BY NOVEL NANO-FUNCTIONAL
PROTEOMICS APPROACHES: NOVEL INSIGHTS FROM THE
GLOBAL PHOSPHOPROTEME
Manuel Fuentes
Poster 10: ASSOCIATION OF GENETIC POLYMORPHISMS WITH DIFFERENTIAL CATALASE
GENE EXPRESSION IN PROGNOSTIC GROUPS OF CHRONIC LYMPHOCYTIC
LEUKEMIA PATIENTS
Marilisa Galasso, Chiara Cavallini, Francesca Maria Quaglia, Ilaria Dando,
Ornella Lovato, Mauro Krampera, Massimo Donadelli, Maria Grazia Romanelli
and Maria Teresa Scupoli
Poster 11: A SMALL MOLECULE INHIBITOR OF ROR1 (KAN0441571C) INDUCED
APOPTOSIS OF IBRUTINIB RESISTANT AND DOUBLE-REFRACTORY CLL CELLS
Amineh Ghaderi, Mohammad-Ali Okhovat, Layung Sekar Sih Wikanthi, Ann
Svensson, Marzia Palma, Johan Schultz, Thomas Olin, Mohammad Hojjat-
Farsangi, Håkan Mellstedt and Anders Österborg
Poster 12: THE BAF CHROMATIN REMODELING COMPLEX IS A NOVEL TARGET OF
SPLICEOSOME DEREGULATION IN SF3B1 MUTATED CHRONIC LYMPHOCYTIC
LEUKEMIA
Daniel Hägerstrand, Diego Cortese, Ying Qu, Amrei Binzer-Panchal, Aron
Skaftason, Viktor Ljungström, Karla Plevova, Evangelia Stalika, Andreas
Agathangelidis, Lydia Scarfo, Marine Armand, Alice Muggen, Neil Kay, Tait
Shanafelt, Davide Rossi, Sarka Pospisilova, Frederic Davi, Anton Langerak, Paolo
Ghia, Kostas Stamatopoulos, Lesley-Ann Sutton and Richard Rosenquist
Poster 13: TWO NOVEL TRNA-DERIVED FRAGMENTS POSSESS CLINICAL UTILITY AS
MOLECULAR BIOMARKERS IN CHRONIC LYMPHOCYTIC LEUKEMIA
Paraskevi Karousi, Katerina Katsaraki, Sotirios G. Papageorgiou, Vasiliki Pappa,
Diamantis C. Sideris, Andreas Scorilas and Christos K. Kontos
Poster 14: ZEBRAFISH “AVATARS” AS A TOOL FOR PERSONALIZED TREATMENT OF CLL
PATIENTS
Ana Logrado, Vanda Póvoa, Filipa Barahona, Joana Caetano, Raquel Lopes,
Sonia Leocádio, Manuel Neves, Paulo Lucio, Rita Fior and Cristina João